Abstract
Summary
1) Polyoma virus hemagglutinin of a hemagglutinating strain 1000 and of a masked strain 8844 were examined by zonal electrophoresis in a density gradient of cane sugar. 2) The masked strain 8844 was unmasked by heat treatment previous to electrophoresis. 3) Both hemagglutinins migrated with the same speed slightly faster than rabbit hemoglobin when tested after an electrophoresis for 3 hours at pH 8.6. 4) Support for the presence of an inhibitor of hemagglutinin in the masked strain 8844 was gained. 5) It appeared that a hemagglutinin-inhibitor separation could be achieved when previously unmasked hemagglutinin was purified by electrophoresis.
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