Abstract
Summary
In the toad Bujo bujo (L.) the pars distalis was inactivated by transplantation to one of the eye muscles or by extirpation of the median eminence. Minimal dose effective in releasing a sloughing factor from inactivated pars distalis was 0.01 I.U. of highly purified or synthetic vasopressin and 0.1 I.U. of synthetic oxytocin. Insipidin, a commercial preparation of vasopressin, and crude extracts of the pars nervosa of whale and toad contained large amounts of the sloughing factor which is probably identical with ACTH.
Get full access to this article
View all access options for this article.