Abstract
Summary
Coe virus dissociates from infected cells, but 25% to 50% of virus is still intracellular at time of maximum cytopathic effect. The virus was relatively stable when exposed to repeated freezing and thawing, and to storage at −70°C, 4°C, and room temperature. At 37°C, 90% of the virus was inactivated within 3 days, and less than 1% of particles were infectious after 20 days. Coe virus is rapidly inactivated at 50°C, but a few particles survive 30 minutes at this temperature. Coe virus is ether resistant and resistant to inactivation at pH 6 to 9.
The excellent technical assistance of Eleanor Sturgill is gratefully acknowledged.
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