Effect of Cholic and Hyodeoxycholic Acids on Metabolism of Exogenous Cholesterol in Mice. ∗

Abstract

Summary

In the female mouse fed a cholesterol-free diet: (1) supplement of 1% cholesterol did not alter liver or carcass cholesterol levels; (2) 1% cholesterol plus 0.5% cholic acid brought about large increases in liver and carcass cholesterol levels; (3) hyodeoxycholic acid reversed the effect of cholic acid and prevented cholesterol accumulation.