Abstract
Summary
Triethylenemelamine (TEM) has been shown to affect adversely the reproductive capacity of male mice by acting on and through spermatozoa without altering their number. motility, or appearance. Females artificially inseminated with spermatozoa from the ductus deferentes and cauda epididymides of treated males showed a marked reduction in per cent fertility as well as litter size. Spermatozoa appeared more sensitive to TEM than late spermatids. No obvious structural changes were induced in testicular elements during treatment. The motility of spermatozoa was unchanged by exposure to a high concentration of TEM in vitro.
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