Absorption of Cholesterol-4-C 14 Oleate ∗

Abstract

Summary

Cholesterol-4-C¹⁴ oleate and cholesterol-4-C¹⁴ were fed in a test meal to lymph fistula rats. The data indicate that free cholesterol was absorbed to a greater extent than esterified cholesterol. This study also provides evidence to support the concept that preliminary hydrolysis is obligatory for absorption of cholesterol esters and that only free cholesterol can enter the intestinal wall. The significance of these findings is discussed.