Effect of Radiation on Distribution of S 35 -Labeled Sulfonamide. ∗

Abstract

Summary

1. Male and female Wistar rats and CAF₁/Jax mice show a reduction in weight of thymus and spleen 48 hours following whole-body irradiation of 150 r. 2. Unlike presence of a tumor in animal body, this irradiation dose does not affect uptake of fluorene-2,7-di-(sulfonamido-2-naphthalene) - S³⁵ by liver and spleen. 3. Significantly different localization of the S³⁵-labeled compound is found in blood cells and thymus of irradiated as compared to nonirradiated male mice.