Abstract
Summary
Administration of large amounts of iodine to hamsters which have hyperplastic goiters produced by an iodine-deficient diet or by a goitrogen results in a morphologic response which is different from that encountered when iodine is given in physiological amounts. An acute inflammatory reaction and a diminution of the accumulation of colloid are found, neither of which has been observed in animals treated with smaller amounts of iodine.
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