Abstract
Summary
1. Normal, adult Z(C3H) mice, connected in parabiotic union with Z(C3H) mice tolerant of Ce tissue, fail to reject homografts of Ce skin. 2. Lack of immunological responsiveness to Ce tissues persists following disruption of parabiotic union. 3. The possibility that failure of transplantation reaction is due to transfer of immunological tolerance to previously unconditioned adult recipient is presented. 4. The implications of these observations are discussed.
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