Abstract
Conclusions
The effect of feeding either desiccated thyroid or propylthiouracil was studied to determine if the former drug resulted in an anticariogenic effect and the latter produced a cariogenic effect in adult rats to the same degree as in weanling animals. Propylthiouracil resulted in significantly more caries than were found in weanling animals, but desiccated thyroid did not reduce the caries experience. Similar histologic changes were found in both thyroid and salivary glands in the adult rats as were found previously in weanlings.
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