Abstract
Summary
Under controlled in vitro conditions (involving equal numbers of human thrombocytes in autologous plasma to which was added an amount of serotonin creatinine sulfate that could be absorbed completely by a few normal specimens in the limited time period allowed), a possibly significant decrease in absorption of serotonin was noted with thrombocytes from patients with non-rheumatoid inflammatory states (p <.02) and with rheumatoid arthritis (p <.05), as compared to individuals with no demonstrable inflammation.
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