Linoleic and Linolenic Acids

Abstract

Summary

1. Oxidation of linoleic and linolenic acids, both randomly labeled with C¹⁴, to CO₂ was compared in a) fasted and glucose-fed normal rats; b) normal and diabetic fed rats; and c) insulin-treated and untreated, fed diabetic rats. 2. Administration of glucose spared oxidation of both linoleic and linolenic acids. 3. Oxidation of linoleic acid by ad lib.-fed diabetic rat exceeded that by similarly fed normal rat. 4. Insulin spared oxidation of polyunsaturated fatty acids in the diabetic rat.