Abstract
Summary
(1) Hesperidin, hesperetin, naringenin, morin and luteolin were fed to young rats to determine their ability to induce thymus involution. Only luteolin was effective, and in this respect resembles quercetin, dihydroquercetin, and eriodictyol. (2) A commercially available preparation, “Calcium Flavonate Glycoside, Lemon,” caused thymus involution. Some relationships between structure and thymolytic action of flavonoids are discussed.
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