Abstract
Summary
An enzyme preparation from mammalian pancreas catalyzes the synthesis of creatine from guanidinoacetate and S-adenosylmethionine. Inasmuch as pancreas, in contrast to liver, can also synthesize the creatine precursor, guanidinoacetate, from arginine plus glycine, it would appear that pancreas may play a unique role in biosynthesis of body creatine.
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