Abstract
Summary
(1) Acquired tolerance of male skin isografts has been produced in females of inbred A and C57Bl (subline 1) strains, over a wide age range, either by injection of viable male spleen cells or by placing females in parabiosis with males. (2) Attention is directed to the importance of age and degree of histocompatibility difference in susceptibility to induction of acquired tolerance. (3) The implications of these observations are discussed.
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