Abstract
Summary
Thin sections of rabbit papillomas reveal pools of dense virus particles in only highly keratinized cells. Viral bodies were readily distinguishable only in papillomas which had been soaked in glycerine-saline for some time. Viral bodies in fresh warts were masked by keratin, melanin and other granules. The bodies are spherical with a non-homogeneous density. They appeared to vary from 25 to 35 mμ in diameter, the most frequent size being 33 mμ. Particles in tissues soaked 1 year or 6 years were identical and equally active in test animals. Sectioned pellets of virus purified by a fluorocarbon process revealed the same particles as those seen in the tissue.
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