Transient Secretion of Phosphate in the Mammalian Kidney ∗

Abstract

Summary

Transient renal responses to close arterial instantaneous injections of NaH₂PO₄ and creatinine were studied in phosphate-loaded dogs. The increment of phosphate excretion per unit injected per one circulation of injected substance was greater than that of creatinine. Such a finding, interpreted as net minimal secretion of phosphate into the renal tubule, was found in 8 consecutive experiments.