Abstract
Summary
No preferential localization of globulin was noted in rejected homotrans-planted canine kidneys studied by fluorescent antibody technic. Indirect variation of this method similarly failed to disclose antibodies exhibiting an affinity for renal structure in serum of recipients exhibiting rejection of renal homotransplants. The fibrin nature of fibrinoid lesions occasionally noted in terminal phases of the rejection phenomenon have been demonstrated. Relationship of pathologic and immunohistochemical alterations of renal homotransplantation rejection and the generalized Shwartzman phenomenon is discussed.
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