Goat Red Blood Cells in Agglutination Test for Infectious Mononucleosis. ∗

Abstract

Summary and Conclusion

Sera from 61 patients showed similar reactions with both sheep and goat rbc in the differential agglutination test for infectious mononucleosis. Twenty-seven sera caused positive differential agglutination with both sheep and goat rbc and reacted in the ox cell hemolysin test. No other sera reacted positively in any of the tests. Goat cells reacted with higher dilution of serum than sheep cells with both patient serums and with 100 normal serums. A positive reaction in goat rbc was of approximately 4-fold higher titer than with sheep rbc. Within limits of these investigations it is concluded that the differential agglutination test with goat rbc and the ox cell hemolysin test gives the same laboratory information for diagnosis of infectious mononucleosis as is obtained from the sheep rbc agglutination test.