Abstract
Summary
1. The bicarbonate ion increases proteolytic activity of rattlesnake venom on gelatin layer of photographic film and of both rattlesnake and water moccasin venom on urea denatured hemoglobin with urea removed. 2. The bicarbonate ion also interferes with inhibition of these proteases by EDTA and penicillamine. 3. EDTA and penicillamine have no significant effect on mouse toxicity of these venoms possibly because of bicarbonate content of body fluids.
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