Abstract
Summary
1) Percent of administered dose in blood, kidney, and salivary gland was determined from 6 minutes to 16 hours after intravenous injection of a mixture of Ca45- Sr85. Salivary glands retained Ca45 in preference to Sr85, reaching a ratio of 4.6:1 at 16 hours. However, the glands showed a distinct retention of Sr83 and contained 3.1 times the concentration in kidney 8 hours after injection. 2) In secretion of saliva, the salivary glands showed less discrimination against Sr in favor of Ca than did uptake by the gland. After administration of tracer amount of Sr85 or of 2.5 meq/kg of normal Sr, ratio of Ca/Sr was only slightly greater in saliva than that in serum.
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