Abstract
Summary
A comparison was made of virulence and immunogenicity of the Vi form of S. paratyphi C and of a non-Vi form selected from the Vi form. Repeated virulence titrations in mice indicate that the Vi-negative mutant is of reduced virulence but does not become avirulent. We have been unable to demonstrate that antibody directed against the Vi antigen plays any role in protecting mice against S. paratyphi C infection.
Get full access to this article
View all access options for this article.