Serum and Plasma Proteins,Lipoproteins and Glycoproteins. III. Hereditary Muscular Dystrophy in Mice. ∗

Abstract

Summary

1. Paper electrophoretic patterns of sera from mice with hereditary form of muscular dystrophy and from normal litter mates as controls showed no change in relative concentrations of the protein fractions themselves, but did indicate a shift in distribution particularly of lipoproteins and, to a smaller extent, of glycoproteins. 2. Concentrations, in plasma, of protein nitrogen, protein-bound lipids (free and esterified cholesterol, phospholipids, esterified fatty acids) and carbohydrates (hexoses, hexosamines and sialic acid) did not vary significantly from those of controls. 3. Results have been compared with those from previous, similar studies on clinical forms of muscular dystrophy and on myopathy of Vit. E-deficiency in rabbits.