Abstract
Summary
1. A method is described for determination of carboxypeptidase in human pancreatic juice. Eighteen samples of pancreatic juice gave an average value for active carboxypeptidase of 3.9 mg % with a range of 2.2–6.2 mg %. Total enzyme concentration representing active enzyme plus procarboxypeptidase gave an average value of 52.8 mg % with a range of 28.3–134.0 mg %. 2. A significant amount of active carboxypeptidase was found in fresh pancreatic juice. High values of active and total carboxypeptidase were found initially postoperatively but these declined on about the third postoperative day. 3. Carboxypeptidase was found to be more stable to autolysis than trypsin.
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