Role of Liver and Kidney in Development of Heparin-induced Lipemia Clearing Activity (LCA). ∗,†

Abstract

Summary

1) Plasma from heparin-injected hepatectomized, CCl₄-cirrhotic and nephrectomized rats exhibited significantly greater lipemia clearing activity than that of heparin-injected normal control animals, when incubated with lipemic plasma in vitro. 2) These results represent indirect evidence for the presence of a clearing factor inactivating system in liver and kidney.