Absorption of H 3 - β -Sitosterol in the Lymph Fistula Rat. ∗

Abstract

Summary

Administration of 44 mg of H³-β-sitosterol to lymph fistula rats and analysis of feces, intestinal contents, intestine, and lymph gave the following results: (1) balance data indicated approximately 40% absorption in 48 hours, (2) there was increased fecal excretion of cholesterol and related sterols, (3) there was considerable uptake of H³-β-sitosterol by the intestinal wall, but essentially no transfer into the lymph. Explanations for the apparent disappearance of H³-β-sitosterol are discussed.