Abstract
Summary
After intravenous injections of fine quartz dust, a serum factor appeared in 8 out of 10 rabbits which agglutinated zymosan to a dilution of 1:256. A similar factor was also noted in occasional uninjected rabbits. This factor differed in certain respects from classical antibodies and appeared to be different from any other hitherto described, to react with zymosan. The conditions of its reaction with zymosan have been studied; they are in some respects similar to those of properdin, and similar to those of conglutinin. In certain respects, however, the factor induced by quartz behaves differently from both properdin and conglutinin. It is not believed that this factor is specifically induced by quartz but rather due to a non-specific immune response.
Get full access to this article
View all access options for this article.