Abstract
In certain cases of retarded development there is faulty skeletal development and disturbed calcium metabolism. The bones are frail and easily fractured; large quantities of calcium are lost through the feces, and the urine is almost free from calcium. It seems probable that the retarded skeletal development is due to the lack of calcium salts available for bone growth. Other cases of retarded development show no such disturbances of calcium metabolism and the bones are of normal solidity. In these cases there is a more fundamental absence of the “tendency to grow” rather than any lack of material for growth.
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