“On the phloridzin test in Bright's disease”

Abstract

Investigation of the action of phloridzin in Bright's disease has a theoretical as well as a practical interest. The mechanism of kidney diabetes is as yet imperfectly understood. The original idea that it was due to a change in the permeability of the kidney epithelium has gradually lost support, and instead there is a growing belief in the hypothesis that, in kidney diabetes, the sugar owes its origin to an exaggerated katabolic condition of the kidney.