Conclusion: The definition of metabolic syndrome needs further refinement and it requires long-term outcome studies to evaluate the various criteria definitively. In general, however, differences of opinion surrounding the syndrome are minor.
References
1.
1. Kylin E.Studien über das Hypertonie-Hyperglykemie-Hyperurikemie syndrome. Zentralblatt für Innere Medizin1923;7:105.
2.
2. Marañon G. ‘Prädiabetische Zustände’. Abhandlungen aus den grenz-gebiete der Inneren Secretion. Wisenschafthliche Verlags Buchhandlung Rudolf Novak. 8 Co. BudapestLeipzig; 1927:12–42.
3.
3. Vague J.La differenciation sexuelle, facteur determinant des formes de l'obesité. Presse Me1947;53:339–40.
5. Reaven GM.Banting Lecture 1988. Role of insulin resistance in human disease. Diabetes1988;37:1595–607.
6.
6. World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications. Report of a WHO consultation, 1999.
7.
7. Balkau B, Charles MA.Comment on the provisional report from the WHO consultation. Diab Med1999;16:442–3.
8.
8. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on DetectionEvaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA2001;285:2486–97.
9.
9. Alberti KG, Zimmet P, Shaw J.The metabolic syndrome: a new worldwide definition. Lancet2005;366:1059–62.
10.
10. Genuth S, Alberti KG, Bennett P. et al. the Expert Committee or the Diagnosis and Classification of Diabetes Mellitus: follow-up report on the diagnosis of diabetes mellitus. Diabetes Care2003;26:3160–7.
11.
11. American Heart Association Scientific Statement.Diagnosis and management of the metabolic syndrome. An American Heart Association/ National Heart Lung and Blood Institute Scientific Statement: executive summary. Circulation2005;112:e285–e290.
12.
12. Ferrannini E, Balkau B, Coppack SW. et al. Insulin resistance, insulin response and obesity as indicators of metabolic risk. J Clin Endocrinol Metab2007(epub ahead of print).
13.
13. Dunstan DW, Zimmet P, Welborn TA. et al. The rising prevalence of diabetes and impaired glucose tolerance. The Australian Diabetes, Obesity and Lifestyle Study. Diabetes Care1001;25:829–34.
14.
14. Sundstrom J, Riserus U, Byberg L, Zethelius B, Lithell H, Lind L.Clinical value of the metabolic syndrome for long-term prediction of total and cardiovascular mortality: prospective, population-based cohort study. BMJ2006;332:878–82.
