1. Young, F.E. (1987). An international framework for biotechnology regulation. Pharmacol. Tech. October. 16-18.
2.
2. Maheshwara, R.K., Czarniecki, C., Dutta, G.P., Puri, S.K., Dhawan, B.N., and Friedman, R. M. (1986). Recombinant human gamma interferon inhibits simian malaria.Infect. Immun.53, 628–630.
3.
3. Schellekens, H., Dereus, A., and Meide, P. H. (1984). The chimpanzee as a odel to test the side effects of human interferons.J. Med. Primatol.13, 235–245.
4.
4. Hendrickx, A.G., and Cukierski, M. A. (1987) Reproductive and developmental toxlcology in nonhuman primates. In: Preclinical Safety, of Biotechnology Products for Human Use. New York: Alan R. Liss, pp. 73–88
5.
5. Palladino, M.A., and Finkle, B. S.(1986). Immunopharmacology of tumor necrosis factors a and b.Tips7, 162–164.
6.
6. Fransen, L., Ruysschaert, M.-R., Van Der Heyden, J., and Fiers, W. (1986). Recombinant tumor necrosis factor: Species specificity for a variety of human and murine transformed cell lines.Cell. Immunol.100, 260–267.
7.
7. Kramer, S.K., Aggarwal, B.A., Eessalu, T.E., Mccabe, S.M., Ferraiolo, B.L., Figari, I.S., and Palladino, M. A. (1988). Characterization of the in vitro and in vivo species preference of human and murine tumor necrosis factor-alpha.Cancer Res.48, 920–925.
8.
8. Shalaby, M.R., Hamilton, E.B., Benninger, A.H., and Marafino, B. J. (1985). In vivo anti-viral activity of recombinant murine gamma interferon.J. Interferon Res.5, 339–345.
9.
9. Chawla, R.K., Parks, J.S., and Rudman, D. (1983). Structural variants of human growth hormone: Biochemical, genetic and clinical aspects.Annu. Rev. Med.34, 519–547.
10.
10. Wilhelmi, A.E. (1975). Chemistry of growth hormone. In: Greep, R.O., and Astwood, E.B., eds. Handbook of Physiology, Vol 4. Washington, D.C.: American Physiolical Society, pp. 59–78
11.
11. Collen, D., Stassen, J.M., and Verstraete, M. (1983). Thrombolysis with human extrinsic (tissue-type) plasminogen activator in rabbits with experimental jugular vein thrombosis.J. Clin Invest.71, 368–376.
12.
12. Gold, H.K., Fallon, J.T., Yasuda, T., Leinbach, R.C., Khaw, B.A., Newell, J.B., Guerrero, J.L., Vislosky, F.M., Hoyng, C.F., Grossbard, E., and Collen, E. (1984). Coronary thrombolysis with recombinant human tissue-type plasminogen activator.Circulation70, 700–707.
13.
13. Korninger, C., and Collen, D. (1981). Studies on the specific fibrinolytic effect of human extrinsic (tissue-type) plasminogen activator in human blood and in various animal species in vitro.Thromb. Haemost.46, 561–565.
14.
14. Lijnen, H.R., Marafino, B.J., and Collen, D. (1984). In vitro fibrinolytic activity of recombinant tissue-type plasminogen activator in the plasma of various primate species.Thromb. Haemostas.52, 308–310.
15.
15. Hotchkiss, A., Refino, C., Deguzman, L., Rigter, B., and Eisert, W. (1987). A new pan species model for the measurement of in vivo thrombolysis. Thromb.Haemostas.58, 107.
16.
16. Donahue, R.E., Wang, E.A., Kaufman, R.J., Foutch, L., Leary, A.C., Witek-Giannetti, J.S., Metzger, M., Hewick, R.M., Steinbrink, D.R., Shaw, G., Kamen, R., and Clark, S.C., (1986). Effects of N-linked carbohydrate on the in vivo properties of human Gm-Csf. Cold Spring Harbor Symp.Quant. Biol.51, 685–692.
17.
17. Ferraiolo, B.L., Moore, J.A., Crase, D., Gribling, P., Wilking, H., and Baughman, R. A. (1988). Pharmacokinetics and tissue distribution of recombinant human tumor necrosis factor-alpha in mice.Drug Metab. Dispos.16, 270–275.