Free accessResearch articleFirst published online 1982-7
Final Report of the Safety Assessment for PEG-75 Lanolin,PEG-20 Lanolin,PEG-27 Lanolin,PEG-30 Lanolin,PEG-40 Lanolin,PEG-50 Lanolin,PEG-60 Lanolin,and PEG-85 Lanolin
PEG Lanolins are the polyethylene glycol ethers of whole lanolin. They are widely used in cosmetics as auxiliary oil/water emulsifiers at concentrations of up to 25%.
PEG Lanolins were found to be nontoxic in acute oral, dermal, and inhalation studies at varying concentrations. They caused little or no eye irritation in rabbits at concentrations of 50-100%. PEG Lanolins at 10-100% caused mild or negligible skin irritation and were reported to be nonsensitizing in guinea pigs. PEG Lanolins were reported to be nonirritating and nonsensitizing in patients at concentrations from 10-60%.
On the basis of the available information, it is concluded that the PEG-75 Lanolin Group is safe as presently used in cosmetic products.
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