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Abstract

A sequential trial of Oxazepam (Adumbran) was carried out on 20 psychiatric outpatients with features of anxiety as part of a personality disorder. A 20 mg. dose t.i.d. was compared with placebo. The result suggests that Oxazepam (Adumbran) is an effective minor tranquilizer and a useful drug in the treatment of psychoneurotic anxiety. The drug appears to have negligible side effects.

References

Armitage

(1960). Sequential Medical Trials. Blackwell Scientific Publications, Oxford.

Baur

(1965). Internistische Behandlung psychovegetativer Stöhrungen. Arztl. Praxis, 17: 908.

Hamilton

(1959). The assessment of anxiety by rating. Brit. J. med. Psychol., 32: 50.

Hoyer

(1965). Erfahrungen mit Adumbran, einem neuen Tranquillizer, in der Allgemeinpraxis. Med. Welt., 1176.

le Gassicke

McPherson

F. M.

(1965). A sequential trial of Wy3498 (Oxazepam). Brit. J. Psychiat., 111: 521.

McPherson

F. M.

le Gassicke

(1965). A single patient, self-controlled and recorded trial of Wy3498. Brit. J. Psychiat., 111: 149.

Siegel

(1956). Nonparametric Statistics for the Behavioural Sciences. McGraw-Hill, New York.

A Sequential Trial of Adumbram (OXAZEPAM)

Abstract

References