Benign sinonasal neoplasms are a heterogeneous group of tumors that present with similar symptoms including nasal obstruction, anosmia, rhinorrhea, and epistaxis. The proper workup and accurate diagnosis is essential for these tumors so that the appropriate treatment plan can be established. In this article of benign sinonasal neoplasms, we discuss their typical clinical presentation, histological and radiographic findings, and treatment options.
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References
1.
MelroyCT and SeniorBA, Benign sinonasal neoplasms: A focus on inverting papilloma. Otolaryngol Clin North Am39:601–617, 2006.
2.
ChiuAGJackmanAHAntunesMB, Radiographic and histologic analysis of the bone underlying inverted papillomas. Laryngoscope116:1617–1620, 2006.
3.
OrlandiRRRubinATerrellJE, Sinus inflammation associated with contralateral inverted papilloma. Am J Rhinol16:91–95, 2002.
4.
RohHJProcopGWBatraPS, Inflammation and the pathogenesis of inverted papilloma. Am J Rhinol18:65–74, 2004.
5.
SyrjanenKJ. HPV infections in benign and malignant sinonasal lesions. J Clin Pathol56:174–181, 2003.
6.
KatoriHNozawaA and TsukudaM.Markers of malignant transformation of sinonasal inverted papilloma. Eur J Surg Oncol31:905–911, 2005.
7.
YousufK and WrightED. Site of attachment of inverted papilloma predicted by CT findings of osteitis. Am J Rhinol21:32–36, 2007.
8.
YousemDMFellowsDWKennedyDW, Inverted papilloma: Evaluation with MR imaging. Radiology185:501–505, 1992.
9.
ShamCLKingADvan HasseltA and TongMC. The roles and limitations of computed tomography in the preoperative assessment of sinonasal inverted papillomas. Am J Rhinol22:144–150, 2008.
10.
KrouseJH. Development of a staging system for inverted papilloma. Laryngoscope110:965–968, 2000.
11.
CannadySBBatraPSSautterNB, New staging system for sinonasal inverted papilloma in the endoscopic era. Laryngoscope117:1283–1287, 2007.
12.
von BuchwaldC and BradleyPJ. Risks of malignancy in inverted papilloma of the nose and paranasal sinuses. Curr Opin Otolaryngol Head Neck Surg15:95–98, 2007.
13.
BusquetsJM and HwangPH. Endoscopic resection of sinonasal inverted papilloma: A meta-analysis. Otolaryngol Head Neck Surg134:476–482, 2006.
14.
WoodworthBABhargaveGAPalmerJN, Clinical outcomes of endoscopic and endoscopic-assisted resection of inverted papillomas: A 15-year experience. Am J Rhinol21:591–600, 2007.
15.
SautterNBCannadySBCitardiMJ, Comparison of open versus endoscopic resection of inverted papilloma. Am J Rhinol21:320–323, 2007.
16.
SauterAMatharuRHörmannK and NaimR.Current advances in the basic research and clinical management of sinonasal inverted papilloma (review). Oncol Rep17:495–504, 2007.
17.
HerfordASStoffellaE and TandonR.Osteomas involving the facial skeleton: A report of 2 cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol115:e1–e6, 2013. [Epub ahead of print June 26, 2012].
18.
RicaldeP and HorswellBB. Craniofacial fibrous dysplasia of the fronto-orbital region: A case series and literature review. J Oral Maxillofac Surg59:157–167, 2001.
OoiEHGlicksmanJTVescanAD and WitterickIJ. An alternative management approach to paranasal sinus fibro-osseous lesions. Int Forum Allergy Rhinol1:55–63, 2011.
21.
SuLWeathersDR and WaldronCA. Distinguishing features of focal cemento-osseous dysplasia and cemento-ossifying fibromas. II. A clinical and radiologic spectrum of 316 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod84:540–549, 1997.
22.
MintzS and VelezI.Central ossifying fibroma: An analysis of 20 cases and review of the literature. Quintessence Int38:221–227, 2007.
23.
SchreiberAVillaretABMaroldiR and NicolaiP.Fibrous dysplasia of the sinonasal tract and adjacent skull base. Curr Opin Otolaryngol Head Neck Surg20:45–52, 2012.
24.
ToyosawaSYukiMKishinoM, Ossifying fibroma vs fibrous dysplasia of the jaw: Molecular and immunological characterization. Mod Pathol20:389–396, 2007.
25.
WenigBMVinhTNSmirniotopoulosJG, Aggressive psam-momatoid ossifying fibromas of the sinonasal region: A clinicopathologic study of a distinct group of fibro-osseous lesions. Cancer76:1155–1165, 1995.
26.
ScholtzAWAppenrothEKammen-JollyK, Juvenile nasopharyngeal angiofibroma: Management and therapy. Laryngoscope111: 681–687, 2001.
27.
BremerJWNeelHB 3rdDeSantoLW and JonesGC. Angiofibroma: Treatment trends in 150 patients during 40 years. Laryngoscope96:1321–1329, 1986.
28.
PryorSGMooreEJ and KasperbauerJL. Endoscopic versus traditional approaches for excision of juvenile nasopharyngeal angiofibroma. Laryngoscope115:1201–1207, 2005.
29.
Neves-PintoRMCarvalhoAAraujoE, Nasal septum giant pyogenic granuloma after a long lasting nasal intubation: Case report. Rhinology43:66–69, 2005.
30.
DuvalMHwangE and KiltySJ. Systematic review of treatment and prognosis of sinonasal hemangiopericytoma. Head Neck DOI: 10.1002/hed.23074. [Epub ahead of print June 25, 2012].
31.
MiddletonLPDurayPH and MerinoMJ. The histological spectrum of hemangiopericytoma: Application of immunohistochemical analysis including proliferative markers to facilitate diagnosis and predict prognosis. Hum Pathol29:636–640, 1998.
