A 49-yr.-old man volunteered to be interviewed about withdrawal effects of alprazolam after having taken alprazolam for 3 mo. During the alprazolam-intake period the subject reported improved sleep though he had not suffered previously from insomnia. Upon withdrawal, he experienced bad mood for a few days and severe insomnia for at least 3 wk. The conclusion was made that more attention should be paid to withdrawal-induced insomnia in case of intermediate-acting benzodiazepines such as alprazolam.
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