In this experiment the arterial pressor response in a dog was classically conditioned. Aseptic surgical procedures were used to implant electrodes chronically in the fastigial nucleus (FN) and cardiovascular instrumentation. The CS was a tone and the US was one of three different intensities of electrical stimulation. It was found that US intensity determined the magnitude of the conditioned pressor response which occurred in conditioning and extinction. These preliminary results indicate that a classical conditioning paradigm can be used to evaluate the degree to which learning can modify the fastigal nucleus-produced arterial pressor response.
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