Two experiments were designed to determine the dose-response relationships between amphetamine injections and the incidence and form of stereotyped behavior. Also, male and female subjects from three different strains of rats (19 Hooded, 4 Tryon Maze Bright, 4 Tryon Maze Dull) were tested. The two experiments demonstrated that the incidence of stereotyped behavior was a monotonic increasing function of dose. Variations in the form of the response to dose are described. Both experiments provided evidence for the existence of constitutional effects. Locomotor activity, which was also measured, displayed dose-response curves which differed consistently from those for most types of stereotyped behavior.
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