6 chimpanzees were given 37 doses of marihuana extract over a 7-mo. period. No long-term effects on baseline operant responding were observed in these animals when compared with the behavior of non-drug control chimpanzees.
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References
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FerraroD. P.GrillyD. M.LynchW. C.Effects of marihuana extract on the operant behavior of chimpanzees. Psychopharmacologia, 1971, 22, 333–351.