Abstract
On the basis of previous running-wheel activity, 48 rats were assigned to four experimental groups: (a) an Insulin Group, which received 2U/kg insulin 30 min. before testing; (b) a Saline Group, which received 2cc/kg saline 30 min. before testing; (c) a Deprived Group, which was food deprived 24 hr. before testing; and (d) a Control Group, which was neither injected nor deprived. Testing consisted of recording the running-wheel activity of the four groups for 15 min. per day for eight days. A significantly higher level of activity was displayed by the Deprived Group, and a significantly lower level of activity was exhibited by the Insulin Group, in comparison with the Saline and Control Groups, which did not differ from each other The decreased activity of the Insulin Group was interpreted as being due to specific neuromuscular actions of the drug.
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