Dogs with chronic salivary fistulae received differential classical salivary conditioning with 1 of 3 CS-US intervals: 2-, 5-, or 15-sec. Differential CR magnitude was greatest in the 5-sec. and least in the 15-sec. group. The effect of ISI was due largely to its influence upon CS+ rather than CS– performance. Baseline, CR strength corrected for baseline, and UR magnitude were reliably greater following reinforced than nonreinforced trials.
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