An experiment and its replication are reported in which the postoperative retention of a successive discrimination problem was studied following destruction of the hippocampus and overlying cortex or of the neocortical areas only. Animals with lesions of the posterolateral neocortex showed severe deficits in performance of the problem. Hippocampectomized Ss were also impaired but their deficit was marked by consistent responding to one arm of the maze, i.e., response fixation.
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References
1.
ClarkC. V.IsaacsonR. L.Effect of bilateral hippocampal ablation on DRL performance. J. comp. physiol. Psychol., 1965, 59, 137–140.
HorelJ. A.BettingerL. A.RoyceJ. G.MeyerD. R.Role of the neocortex in the learning and relearning of two visual habits by the rat. J. comp. physiol. Psychol., 1966, 61, 66–78.
4.
IsaacsonR. L.DouglasR. J.MooreR. Y.The effect of radical hippocampal ablation on acquisition of avoidance responses. J. comp. physiol. Psychol., 1961, 54, 625–628.
JarrardL. E.Hippocampal ablation and operant behavior in the rat. Psychon. Sci., 1964, 2, 115–116.
7.
JarrardL. E.IsaacsonR. L.Runway response perseveration in hippocampectomized rat: determined by extinction variables. Nature, 1965, 207, 109–110.
8.
JarrardL. E.IsaacsonR. L.WickelgrenW. O.Effects of hippocampal ablation and intertrial interval on runway acquisition and extinction. J. comp. physiol. Psychol., 1964, 57, 442–444.
9.
KimbleD. P.The effect of bilateral hippocampal lesions in rats. J. comp. physiol. Psychol., 1963, 56, 273–283.
10.
KimuraD.Effects of selective hippocampal destruction on avoidance behavior in the rat. Canad. J. Psychol., 1958, 56, 273–283.
11.
LashL.Response discriminability and the hippocampus. J. comp. physiol. Psychol., 1964, 57, 251–256.
12.
MacleanP. D.Psychosomatic disease and the “visceral brain:” recent developments bearing on the Papez theory of emotion. Psychosom. Med., 1949, 11, 338–353.
13.
MaierN. R. F.Frustration, the study of behavior without a goal. New York: McGraw-Hill, 1949.
14.
MooreR. Y.Effects of some rhinencephalic lesions on retention of conditioned avoidance behavior in cats. J. comp. physiol. Psychol., 1964, 57, 65–71.
15.
NikiH.The effects of hippocampal ablation on the behavior of the rat. Jap. psychol. Res., 1962, 4, 139–153.
RaphelsonA. C.IsaacsonR. L.DouglasR. J.The effect of limbic damage on the retention and performance of a runway response. Neuropsychologia, in press.
18.
RobertsW. W.DemberW. N.BrodwickM.Alternation and exploration in rats with hippocampal lesions. J. comp. physiol. Psychol., 1962, 55, 695–700.
19.
SchmaltzL. W.IsaacsonR. L.The effects of preliminary training conditions upon DRL 20 performance in the hippocampectomized rat. Physiol. Behav., in press.
20.
SchmaltzL. W.IsaacsonR. L.The retention of a DRL 20 schedule by hippocampectomized rats. J. comp. physiol. Psychol., in press.
21.
ThompsonR.LangerS. K.Deficits in position reversal learning following lesions of the limbic system. J. comp. physiol. Psychol., 1963, 56, 987–995.
22.
ThompsonR.MaunC. F.Jr.The effect of neocortical lesions on retention of a successive brightness discrimination in rats. J. comp. physiol. Psychol., 1961, 43, 326–328.
