Thirteen untreated male schizophrenics were compared with more than 150 post-addicts under three conditions: no-drug, placebo, and 1.5 mcg/kg of LSD-25, using two LSD scales. On an LSD scale that is sensitive to more general drug effects schizophrenics were differentiated from addicts under a no-drug condition, but they were not differentiated from addicts who were given LSD. However, on a more specific LSD scale, addicts under LSD were differentiated from untreated schizophrenics as well as addicts under no-drug, placebo and six other drugs. It appears that there are similarities and differences between responses of schizophrenics and post-addicts to LSD.
Get full access to this article
View all access options for this article.
References
1.
BellevilleR. E.MMPI score changes induced by lysergic acid diethylamide (LSD-25). J. clin. Psychol., 1956, 12, 279–282.
2.
ComreyA. L.MarggraffW.A factor analysis of items on the MMPI schizophrenia scale. Educ. psychol. Measmt, 1958, 18, 301–311.
3.
EysenckH. J.The dynamics of anxiety and hysteria. New York: Praeger, 1957.
4.
HaertzenC. A.A test of a basic assumption of causation in factor analytic theory. changes in correlation between responses and changes in factor composition following the administration of LSD. Unpublished doctoral dissertation, Univer. of Kentucky, 1961.
5.
HaertzenC. A.Criterion analysis of seven drug scales. Paper read at Midwest. Psychol. Assn, Chicago, May, 1962.
6.
HaertzenC. A.Method for direct determination of inverted factor loadings. Psychol. Rep., 1963, 12, 399–402.
7.
HaertzenC. A.HillH. E.Effects of morphine and pentobarbital on differential MMPI profiles. J. clin. Psychol., 1959, 15, 434–437.
8.
HaertzenC. A.HillH. E.Assessing subjective effects of drugs: an index of carelessness and confusion for use with the Addiction Research Center Inventory (ARCI). J. clin. Psychol., 1963, 19, 407–412.
9.
HaertzenC. A.HillH. E.BellevilleR. E.Development of the Addiction Research Center Inventory (ARCI): selection of items that are sensitive to the effects of various drugs. Psychopharmacologia, 1963, 4, 155–166.
10.
HanleyC.Social desirability and response to items from three MMPI scales: D, Sc, K. J. appl. Psychol., 1956, 40, 324–328.
11.
HillH. E.HaertzenC. A.DavisH.An MMPI factor analytic study of alcoholics, narcotic addicts and criminals. Quart. J. stud. Alcohol, 1962, 23, 411–431.
12.
HillH. E.HaertzenC. A.WolbachA. B.MinerE. J.The Addiction Research Center Inventory: standardization of scales which evaluate subjective effects of morphine, amphetamine, pentobarbital, alcohol, LSD-25, pyrahexyl and chlorpromazine. Psychopharmacologia, 1963, 4, 167–183.
13.
HollisterL. E.Drug-induced psychoses and schizophrenic reactions: a critical comparison. Ann. N. Y. Acad. Sci., 1962, 96, 80–88.
14.
JarvikM.Are there any psychotherapeutic or psychotomimetic drugs? In PennesH. H. (Ed.), Psychopharmacology: psychopharmacologic effects on behavior. New York: Hoeber & Harper, 1958. Pp. 203–246.
15.
KassebaumG. G.CouchA. S.SlaterP. E.Factorial dimensions of the MMPI. J. consult. Psychol., 1959, 23, 226–236.
16.
MeesH. L.Preliminary steps in the construction of factor scales for the MMPI. Univer. of Washington, 1959. (Mimeographed report).
17.
SavageC.Variations in ego feeling induced by d-lysergic acid diethylamide (LSD-25). Psychoanal. Rev., 1955, 42, 1–16.
18.
WelshG. S.DahlstromW. R.Basic readings on the MMPI in psychology and medicine. Minneapolis: Univer. of Minnesota Press, 1956.
