LSD: Therapeutic Effects of the Psychedelic Experience

Abstract

Preliminary results of a study of psychedelic therapy are reported. Patients receive LSD and mescaline in a supportive setting following intensive preparation. Subjective questionnaire data from 113 patients reveal a high frequency of claimed benefit, low frequency of negative reaction, and a high relation between claimed benefit and reported “greater awareness of ultimate reality” through the LSD experience. Clinical data on 74 cases including blind ratings of MMPI profiles substantiate the claimed improvement rate. Cases in each of five improvement categories are summarized and before, 2-mo.-after, and 6-mo.-after MMPI data are included. Total improvement rate is above 80%. Follow-ups range from 6 mo. to 2 yr.

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