This report concerned the effect of pre-treatment with hydroxylamine on subsequent susceptibility to metrazol-induced convulsions in laboratory rats susceptible, and those resistant, to sound-induced convulsions. Hydroxylamine failed to consistently protect audio-susceptible animals from doses of metrazol ordinarily effective in eliciting seizures. The reverse was true in the case of animals resistant to sound-induced convulsions.
Get full access to this article
View all access options for this article.
References
1.
GriffithsW. J.Jr.Production of convulsions in the white rat. Comp. psychol. Monogr., 1942, 17, 1–29.
2.
GriffithsW. J.Jr.Effect of hydroxylamine on audiogenic seizures in the laboratory rat. Psychol. Rep., 1963, 13, 755–759.
3.
RobertsE.Metabolism of γ-aminobutyric acid in various areas of brain. In KetyS. S. & ElkesJ. (Eds.), Regional neuro-chemistry.New York: Pergamon Press, 1961. Pp. 324–339.
