Relations between Big Five personality scores aggregated at the American state level and the happiness of Twitter tweet content emanating from each of the 50 American states were explored with the 50 states as the units of analysis. Tweet happiness correlated negatively with Neuroticism, and the relation remained when partial correlation and multiple regression adjusted and controlled for state socioeconomic status, white population percent, and urban population percent. In contrast, state levels of Openness, Conscientiousness, Extraversion, and Agreeableness showed no relation to state levels of the happiness of tweet content.
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