Sweet syndrome (SS) is a rare skin condition that is classically idiopathic in etiology, but can also be triggered by malignancy, drug reaction, or infection. Both chronic hepatitis C infection and antiviral agents for the treatment of hepatitis C have been postulated to be possible triggers of SS.
Objective:
Herein, we present a case of SS in a patient with untreated chronic hepatitis C and cirrhosis but no other significant comorbidities.
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References
1.
SoyluSGulUKilicA. Cutaneous manifestations in patients positive for anti-hepatitis C virus antibodies. Acta Derm Venereol2007;87:49–53, doi:10.2340/00015555-0186.
2.
Abd El HamidMFAmreKSEmamH. Skin manifestations of chronic hepatitis C virus infection in Cairo, Egypt. East Mediterr Health J2009;15:692–700.
3.
SuWPLiuHN. Diagnostic criteria for Sweet's syndrome. Cutis1986;37:167–74.
4.
CohenPR. Sweet's syndrome—a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet J Rare Dis2007;2:34, doi:10.1186/1750-1172-2-34.
5.
WalkerDCCohenPR. Trimethoprim-sulfamethoxazole-associated acute febrile neutrophilic dermatosis: case report and review of drug-induced Sweet's syndrome. J Am Acad Dermatol1996;34 (5 Pt 2):918–23, doi:10.1016/S0190-9622(96)90080-8.
6.
CohenPRKurzrockR. Sweet's syndrome and cancer. Clin Dermatol1993;11:149–57, doi:10.1016/0738-081X(93)90112-P.
7.
von den DrieschP. Sweet's syndrome (acute febrile neutrophilic dermatosis). J Am Acad Dermatol1994;31:535–56; quiz 557–60, doi:10.1016/S0190-9622(94)70215-2.
8.
TanEYosipovitchGGlamYCTanSH. Bullous Sweet's syndrome associated with acute hepatitis B infection: a new association. Br J Dermatol2000;143:914–6, doi:10.1046/j.1365-2133.2000.03810.x.
9.
BazKYaziciACKayaTI. Neutrophilic dermatosis of the hands (localized Sweet's syndrome) in association with chronic hepatitis C and sarcoidosis. Clin Exp Dermatol2003;28:377–9, doi:10.1046/j.1365-2230.2003.01299.x.
10.
YamamotoTOtoyamaKNishiokaK. Unusual annular pustular psoriasis in a patient with type C hepatitis. J Dermatol2000;27:802–3.
11.
SmithJBShenefeltPDSotoOValerianoJ. Pyoderma gangrenosum in a patient with cryoglobulinemia and hepatitis C successfully treated with interferon alfa. J Am Acad Dermatol1996;34(5 Pt 2):901–3, doi:10.1016/S0190-9622(96)90076-6.
12.
DeasyAMWalkerBLaytonAMLaceyCJN. Sweet's syndrome in a patient with haemophilia, HIV and hepatitis C infection. Int J STD AIDS2012;23:e11–3, doi:10.1258/ijsa.2009.009314.
13.
CoelhoJFLourencoSMarquesJ. Neutrophilic dermatosis of the dorsal hands associated with chronic hepatitis C virus infection. Indian J Dermatol Venereol Leprol2008;74:478–80, doi:10.4103/0378-6323.44304.
14.
GheorgheLCotrutaBTrifuV. Drug-induced Sweet's syndrome secondary to hepatitis C antiviral therapy. Int J Dermatol2008;47:957–9, doi:10.1111/j.1365-4632.2008.03724.x.
15.
SgourakisGRadtkeAFouzasI. Corticosteroid-free immunosuppression in liver transplantation: a meta-analysis and meta-regression of outcomes. Transpl Int2009;22:892–905, doi:10.1111/j.1432-2277.2009.00893.x.