There are two rare variants of cutaneous T-cell lymphoma (CTCL) that primarily involve the subcutis. These include subcutaneous panniculitis-like T-cell lymphoma (SPTL) and cutaneous γ/δ T-cell lymphoma.
Objective:
This case report describes the clinical presentation, diagnosis, and treatment of a young man with probable SPTL. A review of recent literature outlining the differences between SPTL and cutaneous γ/δ T-cell lymphoma is discussed.
Conclusion:
The differential diagnosis in patients presenting with subcutaneous nodules and constitutional symptoms should include CTCL.
Get full access to this article
View all access options for this article.
References
1.
WillemzeRJaffeESBurgG. WHO-EORTC classification for cutaneous lymphomas. Blood2005;105:3768–85.
2.
WeenigRHNgCSPerniciarioC. Subcutaneous panniculitis-like T-cell lymphoma: an elusive case presenting as lipomembranous panniculitis and a review of 72 cases in the literature. Am J Dermatopathol200123:206–15.
3.
HoqueSRChildFJWhittakerSJ. Subcutaneous panniculitis-like T-cell lymphoma: a clinicopathological, immunophenotypic and molecular analysis of six patients. Br J Dermatol2003;148:516–25.
4.
WillemzeRJansenPMCerroniL. Subcutaneous panniculitis-like T-cell lymphoma: definition, classification, and prognostic factors: an EORTC cutaneous lymphoma group study of 83 cases. Blood2008;111:838–45. Epub 2007 Oct12.
5.
YimJHKimM-YKimHO. Subcutaneous panniculitis-like T-cell lymphoma in a 26-month-old child with a review of the literature. Pediatr Dermatol2006;23:537–40.
6.
MaLBandarchiBGlusacEJ. Fatal subcutaneous panniculitislike T-cell lymphoma with interface change and dermal mucin, a dead ringer for lupus erythematosus. J Cutan Pathol2005;32:360–5.
