Events at the Vascular Wall: The Molecular Basis of Inflammation

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Whatley RE , Zimmerman GA , Prescott SM , McIntyre TM . Platelet-activating factor and PAF-like mimetics. In: Bell RM , Exton JH , Prescott SM , eds. Lipid Second Messengers. Handbooks of Lipid Research, Vol. 8. New York: Plenum Press; 1996:239–276.

Weyrich AS , McIntyre TM , McEver RP , Prescott SM , Zimmerman GA . Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion: Signal integration and NF-κB translocation. J Clin Invest 1995;95:2297–2303.

Imaizumi T , Albertine KH , Jicha DL , McIntyre TM , Prescott SM , Zimmerman GA . Human endothelial cells synthesize and secrete ENA-78: Relationship to IL-8 and to signaling of PMN adhesion. Am J Respir Cell Mol Biol 1997;17:181–192.

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Patel KD , Zimmerman GA , Prescott SM , McIntyre TM . Novel leukocyte agonists are released by endothelial cells exposed to peroxide. J Biol Chem 1992;267:15168–15175.

Lehr HA , Weyrich AS , Saetzler RK , Jurek A , Arfors KE , Zimmerman GA , Prescott SM , McIntyre TM . Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J Clin Invest 1997;99:2358–2364.

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Marathe GK , Davies SS , Harrison KA , Silva AR , Murphy RC , Castro-Faria-Neto H , Prescott SM , Zimmerman GA , McIntyre TM . Inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines. J Biol Chem 1999;274:28395–28404.

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Stafforini DM , McIntyre TM , Zimmerman GA , Prescott SM . Platelet-activating factor acetylhydrolases. J Biol Chem 1997;272:17895–17898.

Stafforini DM , Prescott SM , Zimmerman GA , McIntyre TM . Mammalian platelet-activating factor acetylhydrolases. Biochim Biophys Acta 1996;1301(3):161–173.

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Stafforini DM , Satoh K , Atkinson DL , Tjoelker LW , Eberhardt C , Yoshida H , Imaizumi T , Takamatsu S , Zimmerman GA , McIntyre TM , Gray PW , Prescott SM . Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase. J Clin Invest 1996;97:2784–2791.

Hiramoto M , Yoshida H , Imaizumi T , Yoshimizu N , Satoh K . A mutation in plasma platelet-activating factor acetylhydrolase (Val279>Phe) is a genetic risk factor for stroke. Stroke 1997;28:2417–2420.

Yamada Y , Ichihara S , Fujimura T , Yokota M . Identification of the G994>T missense in exon 9 of the plasma platelet-activating factor acetylhydrolase gene as an independent risk factor for coronary artery disease in Japanese men. Metabolism 1998;47:177–181.

Ichihara S , Yamada Y , Yokota M . Association of a G994>T missense mutation in the plasma platelet-activating factor acetylhydrolase gene with genetic susceptibility to nonfamilial dilated cardiomyopathy in Japanese. Circulation 1998;98:1881–1885.

Stafforini DM , Numao T , Tsodikov A , Vaitkus D , Fukuda T , Watanabe N , Fueki N , McIntyre TM , Zimmerman GA , Makino S , Prescott SM . Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma. J Clin Invest 1999;103:989–997.

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