Thioureas are used as additives in rubber products and as antidegradants for natural rubber latex. They are an uncommon cause of allergic contact dermatitis. This case represents an example of occupational allergic contact dermatitis solely from thioureas in rubber products and no cross-reactivity with other rubber allergens. Standard patch tests may fail to detect thiourea-induced allergic contact dermatitis, so clinicians should consider thiourea sensitization in rubber allergy.
Get full access to this article
View all access options for this article.
References
1.
SakataS, CahillJ, NixonR. Allergic contact dermatitis to thiourea in a neoprene knee brace. Australas J Dermatol, 2006; 47:-.
2.
WarshawEM, CookJW, BelsitoDV, et al.Positive patch-test reactions to mixed dialkyl thioureas: cross-sectional data from the North American Contact Dermatitis Group, 1994 to 2004. Dermatitis, 2008; 19:190-201.
3.
GeierJ, LessmannH, UterW, et al.Occupational rubber glove allergy: results of the information network of departments of dermatology (IVDK), 1995-2001. Contact Dermatitis, 2003; 48:39-44.
4.
ComfereNI, DavisMD, FettDD. Patch-test reactions to thioureas are frequently relevant. Dermatitis, 2005; 16:121-3.