Allergens Retained in Clothing

Abstract

Background:

Some patients state compliance with avoidance of identified allergens, yet have persistent dermatitis in areas under tight-fitting clothing.

Objective:

To analyze a series of such cases to identify allergens most likely retained in clothing.

Methods:

Review of contact dermatitis clinic cases and identification of type and formula weight of allergens involved.

Results:

High-formula-weight allergens and allergens present in medicament ointments are difficult to dissolve in laundry detergent and water and may be retained in clothing.

Conclusion:

Retention of allergens in clothing, even after washing, may explain recalcitrant dermatitis in a patient who states compliance with avoidance of a seemingly relevant allergen. Dermatologists should consider the possibility of allergen retention in clothing whenever a patient has only partial clearing after at least 1 month of attempted compliance with avoidance of identified allergens. Purchase of new clothing may be required to clear allergic contact dermatitis in this situation.